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English to German: CME - Novel therapies for multiple sclerosis, clinical trial results General field: Medical Detailed field: Medical: Pharmaceuticals
Source text - English Ocrelizumab is a humanized anti-CD20 B cell monoclonal antibody currently in phase 3 clinical trials for RRMS and primary progressive MS (PPMS). In a phase 2 randomized, placebo- and active-controlled trial in RRMS, ocrelizumab decreased the number of gadolinium-enhancing lesions by 89% with the 600-mg dose and by 96% with the 2000-mg dose.[4] To assess the effects of ocrelizumab on B cells, ocrelizumab was administered at doses of 0, 10, 50, and 100 mg/kg to cynomolgus monkeys.[5] After 2 infusions given 2 weeks apart, peripheral blood B cells (CD3-CD40+) were suppressed to undetectable levels. Recovery with the 10-mg/kg dose began at week 6 and with the 50-mg/kg and 100-mg/kg doses at week 14.
Translation - German Ocrelizumab ist ein humanisierter monoklonaler Anti-CD 20-B-Zell-Antikörper, der zurzeit in klinischen Phase-III-Studien auf den Einsatz bei RRMS und primär progredienter MS (PPMS) untersucht wird. In einer randomisierten, placebo- und aktiv kontrollierten Phase-II-Studie zu RRMS senkte Ocrelizumab die Anzahl der Gadolinium-anreichernden Läsionen um 89% in der 600mg-Dosierung und um 96% in der 2000mg-Dosierung.[4] Zur Beurteilung der Wirkungen von Ocrelizumab auf B-Zellen, wurde Ocrelizumab in Dosierungen von 0, 10, 50, und 100 mg/kg an Javaneraffen verabreicht.[5] Nach zwei Infusionen im Abstand von zwei Wochen waren die peripheren B-Zellen (CD3-CD40+) auf nicht nachweisbare Konzentrationen supprimiert. Eine Erholung begann bei der 10 mg/kg-Dosis in der 6. Woche und bei den 50 mg/kg und 100 mg/kg-Dosierungen in der 14. Woche.
English to German: Script for a Language Program General field: Other Detailed field: Education / Pedagogy
Source text - English Hanna: German television polls show that many people voted for the AfD as sort of a protest. In fact, 60 percent said they voted “against all other parties” -- only 34 percent said they voted for the AfD out of conviction. This is very different from other parties…
Phillip: Does it matter? The far right is part of the Bundestag now. And they certainly won’t be quiet! Let’s hope that Merkel’s coalition, and the Social Democrats, manage to sideline them...
Translation - German Hanna: Umfragen des deutschen Fernsehens zeigen, dass viele Leute AfD aus Protest gewählt haben. 60 Prozent sagen, sie hätten damit „gegen alle anderen Parteien“ gestimmt. Nur 34 Prozent sagen, sie hätten AfD aus Überzeugung gewählt. Das ist schon anders als bei den anderen Parteien ...
Phillip: Und? Spielt das eine Rolle? Fakt ist, dass die Rechten jetzt im Bundestag sitzen. Und sie werden dort mit Sicherheit nicht Däumchen drehen. Hoffentlich gelingt es Merkels Koalition und den Sozialdemokraten, sie ins Abseits zu drängen ...
I am a scientist by training (Ph.D. in Cell Biology) who after several years in biomedical research decided to trade her lab coat for a laptop, an ergonomic keyboard and a stack of dictionaries.
I have been working as a freelance translator since 2007 and specialize in medical translations, in particular IFUs for medical devices, in vitro diagnostics and pharmaceuticals; clinical study protocols and reports, patient information and continuing medical education for physicians. I also have extensive experience with quality management documentation, corporate communications, public relations and marketing materials.
In addition, I have been the German translator and reviewer of content and grammar for News in Slow German, a German language learning program since its beginnings in 2016.
I particularly enjoy translating marketing and advertising texts that challenge my creativity.
I am an ATA-certified translator (English into German).
This user has earned KudoZ points by helping other translators with PRO-level terms. Click point total(s) to see term translations provided.
Keywords: medical, biology, biomedical research, life science, medical devices, infectious diseases, drug development, user manual, parenting, Medizin. See more.medical,biology,biomedical research,life science,medical devices,infectious diseases,drug development,user manual,parenting,Medizin,Biologie,Biomedizinforschung,Forschung,Naturwissenschaft,Medizintechnik,medizinische Geräte,Infektionskrankheiten,Medikamentenentwicklung,Arzneimittelentwicklung,marketing,corporate communications,transcreation,english to german translator,Boston,. See less.
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