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English to Russian: Вакцинация ВИЧ-инфицированных лиц против вирусного гепатита В General field: Medical Detailed field: Medical (general)
Source text - English The long-term protection of HBV vaccine in HIV-infected individuals remains unknown, as well as correlates for protection in this patient population. Therefore, we assessed risk factors for HBV infection, including HBV vaccination, in our prospectively followed multicenter cohort, and evaluated risk factors for HBV infection among vaccine recipients, including vaccine response.
Conclusion: Overall, HBV vaccination was not associated with reduced risk of HBV infection in our cohort of HIV-infected individuals. However, the small subset of vaccinees with a positive vaccine response may have had reduced HBV infection risk, including chronic disease. Improvements in vaccine delivery and immunogenicity are needed to increase HBV vaccine effectiveness in HIV-infected patients.
Translation - Russian Долгосрочная эффективность вакцинации против вирусного гепатита В при наличии ВИЧ-инфекции все еще не установлена, как и факторы, которые на нее влияют. В связи с вышесказанным наше проспективное многоцентровое когортное исследование было посвящено изучению факторов риска развития вирусного гепатита В среди лиц с ВИЧ-инфекцией (в частности, значимости вакцинации против этого заболевания) и среди вакцинированных лиц с ВИЧ-инфекцией (в частности, значимости наличия серологического ответа на вакцинацию).
Выводы: В целом вакцинация против вирусного гепатита В не снижала риск его развития у ВИЧ-инфицированных лиц исследовавшейся нами когорты. Однако в небольшой части случаев, когда был достигнут положительный серологический ответ на вакцинацию, она все же имела защитный эффект в отношении предупреждения HBV-инфекции, в том числе хронической. Чтобы повысить эффективность вакцинации ВИЧ-инфицированных лиц против вирусного гепатита В, необходимо увеличить их охват вакцинацией и усилить иммуногенность вакцины.
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Experience
Years of experience: 18. Registered at ProZ.com: Dec 2009.
LANGUAGE PAIRS: English → Russian/Ukrainian (Native)
Fields of specialization:
Pharmacy:
Summary of Product Characteristics, Leaflets, Package Inserts and Labels, Periodic Safety Update Reports, Drug Registration Documentation, Nonclinical Study Reports, Marketing Brochures
Clinical study documentation:
Clinical Trial Protocols, Case Report Forms, Informed Consent Forms, Investigator Brochures
Human medicine:
Scientific publications in the field of cardiology, endocrinology, dermatology, gastroenterology,
oncology, HIV infection
EXPERIENCE:
Healthcare experience:
Since 2004 - Endocrinologist in Ambulatory Center "Eskulap", Alchevsk, Ukraine
2001-2004 - Pediatrician in Alchevsk municipal children's hospital, Ukraine
Medical translation experience: ~400 000 words per year
Since 2008 - freelance translator translation agencies, medical journals, medical publishing houses
EDUCATION:
2001 - MD in general medicine (Lugansk State Medical University, Ukraine)
2004 - MD in endocrinology (Kharkiv Medical Academy of Postgraduate Education, Ukraine)
Equipment: Notebook MSI CX600, Intel Core 2 Duo T6600 2.2 GHz Processor, RAM 2GB, 320GB SATA HDD
Software: MS Office, Adobe Acrobat, ABBYY FineReader
