May 20, 2023 13:07
1 yr ago
15 viewers *
English term
drug space
English to Polish
Science
Chemistry; Chem Sci/Eng
chemia leków
On average six new ring systems enter drug space each year and approximately 28% of new drugs contain a new ring system.
The chemical novelty in drugs has been analyzed to assess how many new rings
are used per drug and the distribution over time as the rings enter
drug space. We make the distinction here between druglike space (often measured by a whole molecule similarity score), which we
define as molecules having similar properties to drugs, and drug
space where the exact ring has been used in a drug.
The chemical novelty in drugs has been analyzed to assess how many new rings
are used per drug and the distribution over time as the rings enter
drug space. We make the distinction here between druglike space (often measured by a whole molecule similarity score), which we
define as molecules having similar properties to drugs, and drug
space where the exact ring has been used in a drug.
Proposed translations
(Polish)
2 | strefa/sektor/obszar/przestrzeń leków/farmaceutyków | Jacek Rogala |
3 | przestrzeń chemiczna leku | Andrzej Ziomek |
Proposed translations
2 hrs
Selected
strefa/sektor/obszar/przestrzeń leków/farmaceutyków
propozycje
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Note added at 4 hrs (2023-05-20 17:25:12 GMT)
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Obszar leków recepturowych jest przedmiotem szczegółowej kontroli Narodowego Funduszu Zdrowia.
at:
https://mgr.farm/aktualnosci/leki-recepturowe-i-inflacja-far...
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Note added at 22 hrs (2023-05-21 11:54:56 GMT)
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Drug-like chemical space is defined as those compounds that have pharmacokinetic properties to survive the completion of human phase I clinical trials.
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Note added at 4 hrs (2023-05-20 17:25:12 GMT)
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Obszar leków recepturowych jest przedmiotem szczegółowej kontroli Narodowego Funduszu Zdrowia.
at:
https://mgr.farm/aktualnosci/leki-recepturowe-i-inflacja-far...
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Note added at 22 hrs (2023-05-21 11:54:56 GMT)
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Drug-like chemical space is defined as those compounds that have pharmacokinetic properties to survive the completion of human phase I clinical trials.
3 KudoZ points awarded for this answer.
22 hrs
przestrzeń chemiczna leku
.
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Note added at 22 hrs (2023-05-21 11:41:57 GMT)
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space -> przestrzeń
ring -> pierścień
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Note added at 23 hrs (2023-05-21 12:07:34 GMT)
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http://www.sbc.org.pl/Content/94997
4.2.1 PRZESTRZEŃ CHEMICZNA I FARMAKOLOGICZNA AZANAFTALENÓW
Przestrzeń chemiczną azanaftalenów zdefiniowano jako pulę związków organicznych
zawierających fragment mono- lub diazanaftalenowy jako podstrukturę.
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Note added at 22 hrs (2023-05-21 11:41:57 GMT)
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space -> przestrzeń
ring -> pierścień
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Note added at 23 hrs (2023-05-21 12:07:34 GMT)
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http://www.sbc.org.pl/Content/94997
4.2.1 PRZESTRZEŃ CHEMICZNA I FARMAKOLOGICZNA AZANAFTALENÓW
Przestrzeń chemiczną azanaftalenów zdefiniowano jako pulę związków organicznych
zawierających fragment mono- lub diazanaftalenowy jako podstrukturę.
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