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Source text - English Current recommendations by the National Institutes of Health in a 2000 consensus statement suggest that "adjuvant hormonal therapy should be recommended to women whose breast tumors contain hormone receptor protein, regardless of age, menopausal status, involvement of axillary lymph nodes, or tumor size" (7). Tamoxifen is the most commonly used hormonal therapy, with data supporting a five-year course of therapy. In general, all older women with ER+ or PgR+ tumors should be considered candidates for hormonal adjuvant therapy. Adjuvant hormonal therapy is not currently recommended for ER-negative breast tumors (8).
Cytotoxic chemotherapy represents the second systemic therapy available to women in the adjuvant setting. The most common adjuvant chemotherapy choices include cyclophosphamide, methotrexate, and fluorouracil (CMF), and doxorubicin and cyclophosphamide (AC). Individual tumor characteristics (such as HER2/neu status) are currently under study in determining their influence on adjuvant chemotherapy choice. In addition, the use of agents such as taxanes and trastuzumab (a monoclonal antibody that targets HER2) in the adjuvant setting is currently under intensive investigation given the success of these agents in the advanced breast cancer treatment setting.
Translation - Spanish Las actuales recomendaciones de los Institutos Nacionales de Salud de EE. UU. recogidas en una declaración de consenso en el año 2000 sugieren que “debe recomendarse el tratamiento hormonal adyuvante a las mujeres cuyos tumores mamarios contengan la proteína del receptor hormonal, independientemente de la edad, estado menopáusico, afectación de los ganglios linfáticos axilares o tamaño del tumor” (7). El tamoxifeno es el fármaco usado más habitualmente en el tratamiento hormonal y se dispone de datos que respaldan su uso durante un ciclo de 5 años. En general, todas las mujeres de edad avanzada cuyos tumores tengan RE o RPg deben considerarse idóneas para recibir tratamiento adyuvante hormonal. En la actualidad no se recomienda el tratamiento hormonal para los tumores que carecen de RE (8).
La quimioterapia citotóxica representa el segundo tratamiento sistémico disponible para las mujeres dentro del marco del tratamiento adyuvante. Las opciones de quimioterapia adyuvante más habituales son la combinación de ciclofosfamida, metotrexato y fluorouracilo (CMF) y la combinación de doxorrubicina y ciclofosfamida (AC). Actualmente se están estudiado características tumorales individuales (tales como el estado HER2/neu) para determinar su influencia sobre la elección de la quimioterapia adyuvante. Además, se está investigando activamente el uso de otros fármacos, como los taxanos y el trastuzumab (un anticuerpo monoclonal que actúa selectivamente sobre HER2), en el tratamiento adyuvante dado el éxito de éstos fármacos en el tratamiento del cáncer de mama avanzado.
English to Spanish (Escuela Oficial de Idiomas de Madrid)
Memberships
TREMEDICA, Unión de Correctores (UniCo), AERTeM (Asociación Española de Redactores de Textos Médicos (, MEDTRAD - Grupo de Medicina y Traducción (Group on Medicine and, ASETRAD
Software
Adobe Acrobat, Adobe Photoshop, Microsoft Excel, Microsoft Word, Powerpoint, QuarkXPress, SDLX, Trados Studio
MEDICINE - PHARMACEUTICS - MEDICAL DEVICES - IVD DEVICES -
HEALTH SCIENCES - LIFE SCIENCES - FORENSIC MEDICINE
ENGLISH INTO SPANISH TRANSLATIONS
SPANISH EDITING/PROOFREADING
LOCALIZATION INTO EUROPEAN SPANISH
LINGUISTIC CONSULTANCY
SPANISH MEDICAL WRITING
QUALITY ACCURATE TRANSLATIONS READING LIKE ORIGINALS
EDITED TEXTS FREE OF GRAMMAR, TYPO, STYLE OR CONTENT ERRORS
by a TRANSLATOR & EDITOR with
· wide medical background (M.D.Ph.D. with years of medical practice and continuing education; forensic doctor)
· profound knowledge of medical terminology and language both in English and Spanish
· writing, proofreading and editing skills with excellent knowledge of Spanish grammar, syntax and orthographic rules
EXTENSIVE EXPERIENCE, EXCLUSIVELY IN
MEDICINE, PHARMACEUTICS AND ALLIED SCIENCES:
. Medical books: 16 books translated and 10 books edited on Neuropsychopharmacology, Psychiatry, Cardiology, Pain, Pneumology, Otolaringology, Family Medicine, and Veterinary Medicine. . Medical journals: more than 100 medical papers translated and edited/proofread for over 30 major peer-reviewed medical journals. . Medical papers from journals and proceedings of medical meetings: over 400 articles and abstracts translated. . Drug registration dossiers, expert reports on new drug applications, summaries of product characteristics and clinical studies (from protocols to final reports) for leading pharmaceutical companies. Medical and surgical devices: more than 500 manuals translated/edited for over 70 manufacturers of CSF drainage systems, coronary dilatation catheters, peripheral dilatation catheters, debulking systems, embolization coils, drug eluting stent systems, blood oxigenators, pressure guide wires, torques, ventricular catheters, ventricular assist systems, peritoneal catheters, continuous nerve block catheters, abscess drainage catheters, intra-aortic balloon products, biliary stents, coronary stents, ureteral stents, infusion catheters, endovascular grafts, embolic protection systems, feeding tubes, intraosseus infusion needle sets, biopsy systems, rotating hemostatic valves, adaptors, connectors, sutures, syringes, ultrasound imaging system, blood and fluid warmers, electrocautery systems, pacing systems, ventilators, bronchial monitoring, suction systems, pain relieve systems, finger and ear sensors.. In vitro diagnostic devices: over 60 manuals translated for leading manufacturers of analyzers, calibrators, cholesterol assays, chromatography, HCV assays, genotype assays, genotyping software, pool and spa test strips, HIV assays, Pap tests, sampling, processing and transport of biological specimens, tacrolimus assay, West Nile virus assay, etc. . Orthopaedical devices: over 25 manuals translated on acrylic resins, bone biopsy systems, bone cements, curettes, osteotomy sytems, splints, stylets, toe fillers, toe M-P joints, trocars, etc.
. Dentistry: more than 30 manuals translated/edited on dental implants. . Patient questionnaires: Translation, review, linguistic validation and patient cognitive debriefing of self-reported outcome measures for administration in multinational clinical trials. . Material safety data sheets (MSDS): over 250 MSDS translated for chemical and oil companies. . Lab procedures and protocols. Health-related web sites· Medical records
· Patient information sheets
. Informed consent forms
. Patient education material
· Medical reports
· Medical meeting programmes
· Brochures, advertising and promotional literature
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