May 2 21:25
2 days ago
Spanish term
mitosis atípicas 0-2 (csf)
Spanish to English
Medical
Medical (general)
anatomic pathology / histology
From an anatomic pathology report of a biopsy taken from a tumor in the pancreas, the report is from a clinic in Mexico.
Any ideas for what "csf" may refer to?
Descripción microscópica:
(...)
"Las células son intermedias, con hipercromasia, pleomorfismo moderado contorno nuclear irregular, mitosis atípicas 0-2 (csf), necrosis (30%) y citoplasma esinófilo." Written as is, with "csf" in lower case.
My thinking would be maybe "campo de alto poder"/"campo de gran aumento" (high-power field, but the abbreviation doesn't fit) or "cytostatic factor" or "colony-stimulating factor", but from my research, none of these seem to apply in the context.
And what would the 0-2 refer to? There are a total of eight cassettes (cápsulas) submitted, if that's relevant.
For U.S. English (though I expect that makes no difference here). Thank you.
Any ideas for what "csf" may refer to?
Descripción microscópica:
(...)
"Las células son intermedias, con hipercromasia, pleomorfismo moderado contorno nuclear irregular, mitosis atípicas 0-2 (csf), necrosis (30%) y citoplasma esinófilo." Written as is, with "csf" in lower case.
My thinking would be maybe "campo de alto poder"/"campo de gran aumento" (high-power field, but the abbreviation doesn't fit) or "cytostatic factor" or "colony-stimulating factor", but from my research, none of these seem to apply in the context.
And what would the 0-2 refer to? There are a total of eight cassettes (cápsulas) submitted, if that's relevant.
For U.S. English (though I expect that makes no difference here). Thank you.
Proposed translations
(English)
3 +4 | 0-2 atypical mitoses per high dry field (HDF) |
Charles Davis
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4 -1 | 0-2 atypical mitoses per high-power field (HPF) |
Vinicius Casseb
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References
csf = campo(s) a seco fuerte |
Charles Davis
![]() |
Proposed translations
-1
10 mins
0-2 atypical mitoses per high-power field (HPF)
Mitotic rate expresses the number of mitotic figures in a defined microscopic area; “atypical” flags abnormal (often multipolar) figures that imply higher malignant potential. “0–2 … (csf)” therefore records a low frequency of atypical mitoses.
Example sentence:
The cells are intermediate in size, with hyperchromasia, moderate pleomorphism, irregular nuclear contours, 0–2 atypical mitoses per high-power field (HPF), 30 % necrosis, and eosinophilic cytoplasm.
Note from asker:
OK, but why CSF? |
+4
11 hrs
0-2 atypical mitoses per high dry field (HDF)
I am not an expert and I wouldn't be surprised if "high-power field" meant the same thing in practice, but still, since it says "csf", which means "campo seco fuerte" (see reference below), and since "per high dry field" is used in a number of authentic scientific texts apparently by native English-speaking authors, I think it may be worth doing it this way. As indicated in my reference, "seco", or "dry" refers to the non-use of immersion oil, which produces a sharper image with high-power lenses, by counteracting refraction:
"By placing a substance such as immersion oil with a refractive index equal to that of the glass slide in the space filled with air, more light is directed through the objective and a clearer image is observed. [...] Notice the difference in image quality between the images captured dry versus those captured with immersion oil."
https://www.microscopeworld.com/t-using_microscope_immersion...
So in principle "dry" does add meaning.
Anyway, here are some examples of the expression:
"In the appropriate area for performing a white blood cell estimate, there are 1-2 white cells seen per high dry field."
https://quizlet.com/322386205/exam-1-review-questions-flash-...
"leucocytes, 3-5 per high dry field, erythrocytes-30-so per high dry field".
https://archive.org/details/in.ernet.dli.2015.71298/page/n29...
"Mitoses (fig. 4-1) ranged from 2-6 per high power dry field."
https://www.askjpc.org/wsco/wsc/wsc07/07WSC04.pdf
"LABORATORY ABBREVIATIONS [...]
Hdf - High Dry Field"
Department of Pathology and Laboratory Medicine, Rochester General Hospital
https://d2xk4h2me8pjt2.cloudfront.net/webjc/attachments/245/...
"There are various methods for reporting the mitotic activity, including number of mitoses visible per certain number of high, dry microscopic fields or the number of mitoses present in a certain number of cells (mitotic index)."
https://www.sciencedirect.com/topics/neuroscience/mitosis-ra...
"By placing a substance such as immersion oil with a refractive index equal to that of the glass slide in the space filled with air, more light is directed through the objective and a clearer image is observed. [...] Notice the difference in image quality between the images captured dry versus those captured with immersion oil."
https://www.microscopeworld.com/t-using_microscope_immersion...
So in principle "dry" does add meaning.
Anyway, here are some examples of the expression:
"In the appropriate area for performing a white blood cell estimate, there are 1-2 white cells seen per high dry field."
https://quizlet.com/322386205/exam-1-review-questions-flash-...
"leucocytes, 3-5 per high dry field, erythrocytes-30-so per high dry field".
https://archive.org/details/in.ernet.dli.2015.71298/page/n29...
"Mitoses (fig. 4-1) ranged from 2-6 per high power dry field."
https://www.askjpc.org/wsco/wsc/wsc07/07WSC04.pdf
"LABORATORY ABBREVIATIONS [...]
Hdf - High Dry Field"
Department of Pathology and Laboratory Medicine, Rochester General Hospital
https://d2xk4h2me8pjt2.cloudfront.net/webjc/attachments/245/...
"There are various methods for reporting the mitotic activity, including number of mitoses visible per certain number of high, dry microscopic fields or the number of mitoses present in a certain number of cells (mitotic index)."
https://www.sciencedirect.com/topics/neuroscience/mitosis-ra...
Peer comment(s):
agree |
philgoddard
6 mins
|
Thanks again, Phil
|
|
agree |
Paul Ryan
: cosnautos also gives campo seco y fuerte
2 hrs
|
Thanks, Paul! I forgot to check Cosnautas
|
|
agree |
Andrés Martínez
: Well documented.
3 hrs
|
Many thanks, Andrés
|
|
agree |
neilmac
22 hrs
|
Thanks, Neil :-)
|
Reference comments
10 hrs
Reference:
csf = campo(s) a seco fuerte
"toma en cuenta el número de mitosis por 10 campos a seco fuerte"
Tabla 1
"CSF: campos a seco fuerte"
https://www.revistagastroenterologiamexico.org//es-caracteri...
"con núcleos pleomórficos e hipercromáticos, nucléolo prominente y numerosas mitosis (cuatro por campo a seco fuerte)"
https://www.redalyc.org/pdf/4577/457745496018.pdf
Google AI: "La frase "mitosis por campo a seco fuerte" se refiere a la observación de la mitosis (división celular) en un preparado de células bajo un microscopio óptico sin utilizar un objetivo de inmersión en aceite ni tinción alguna. En otras palabras, se trata de observar la mitosis "a campo seco" utilizando un objetivo de alto poder de aumento, pero sin el uso de aceite."
https://www.google.com/search?q="mitosis" "por campo a seco ...
Previous question
Spanish term or phrase: se observan linfócitos (5-10 por campo a "seco fuerte.")
English translation: under high dry lens
Entered by: liz askew
https://www.proz.com/kudoz/spanish-to-english/biology-tech-c...
Tabla 1
"CSF: campos a seco fuerte"
https://www.revistagastroenterologiamexico.org//es-caracteri...
"con núcleos pleomórficos e hipercromáticos, nucléolo prominente y numerosas mitosis (cuatro por campo a seco fuerte)"
https://www.redalyc.org/pdf/4577/457745496018.pdf
Google AI: "La frase "mitosis por campo a seco fuerte" se refiere a la observación de la mitosis (división celular) en un preparado de células bajo un microscopio óptico sin utilizar un objetivo de inmersión en aceite ni tinción alguna. En otras palabras, se trata de observar la mitosis "a campo seco" utilizando un objetivo de alto poder de aumento, pero sin el uso de aceite."
https://www.google.com/search?q="mitosis" "por campo a seco ...
Previous question
Spanish term or phrase: se observan linfócitos (5-10 por campo a "seco fuerte.")
English translation: under high dry lens
Entered by: liz askew
https://www.proz.com/kudoz/spanish-to-english/biology-tech-c...
Peer comments on this reference comment:
agree |
philgoddard
1 hr
|
Thanks, Phil
|
|
agree |
neilmac
1 day 50 mins
|
Thanks, Neil
|
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